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When the environment remains relatively constant, stabilizing selection tends to maintain genetic traits that represent the optimal average for a population (2).When environmental conditions permanently change, evolutionary discordance arises between a species’ genome and its environment, and stabilizing selection is replaced by directional selection, moving the average population genome to a new set point (1, 2).Taken together, these data indicate that dairy foods, on an evolutionary time scale (Figure 1 Because wild cereal grains are usually small, difficult to harvest, and minimally digestible without processing (grinding) and cooking, the appearance of stone processing tools in the fossil record represents a reliable indication of when and where cultures systematically began to include cereal grains in their diet (7).
Additionally, mixtures of foods listed in Table 1 make up the ubiquitous processed foods (eg, cookies, cake, bakery foods, breakfast cereals, bagels, rolls, muffins, crackers, chips, snack foods, pizza, soft drinks, candy, ice cream, condiments, and salad dressings) that dominate the typical US diet.
Hominins, like all mammals, would have consumed the milk of their own species during the suckling period.
Osteoporotic hip fractures are associated with a 20% excess mortality in the year after fracture (17).
Cancer is the second leading cause of death (25% of all deaths) in the United States, and an estimated one-third of all cancer deaths are due to nutritional factors, including obesity (18). Similar to historically studied hunter-gatherers (20, 21), there would have been no single universal diet consumed by all extinct hominin species.
Preceding the Industrial Revolution, all cereals were ground with the use of stone milling tools, and unless the flour was sieved, it contained the entire contents of the cereal grain, including the germ, bran, and endosperm (35).
With the invention of mechanized steel roller mills and automated sifting devices in the latter part of the 19th century (35), the nutritional characteristics of milled grain changed significantly because the germ and bran were removed in the milling process, leaving flour comprised mainly of endosperm of uniformly small particulate size (35, 36).Initially, when permanent environmental changes occur in a population, individuals bearing the previous average status quo genome experience evolutionary discordance (2, 3).In the affected genotype, this evolutionary discordance manifests itself phenotypically as disease, increased morbidity and mortality, and reduced reproductive success (1-3).There is growing awareness that the profound changes in the environment (eg, in diet and other lifestyle conditions) that began with the introduction of agriculture and animal husbandry ≈10000 y ago occurred too recently on an evolutionary time scale for the human genome to adjust.In conjunction with this discordance between our ancient, genetically determined biology and the nutritional, cultural, and activity patterns of contemporary Western populations, many of the so-called diseases of civilization have emerged.In particular, food staples and food-processing procedures introduced during the Neolithic and Industrial Periods have fundamentally altered 7 crucial nutritional characteristics of ancestral hominin diets: Evolution acting through natural selection represents an ongoing interaction between a species’ genome and its environment over the course of multiple generations.Tags: Adult Dating, affair dating, sex dating